青年冠心病患者危险因素分析

目的　探讨 5 0岁以下冠心病患者危险因素 ,对高危青年人的冠心病一级预防提供参考。方法　根据 15 6例冠状动脉造影结果将 5 0岁以下行冠脉造影者分为冠心病组 (89例 )和非冠心病组 (6 7例 ) ,收集临床心血管危险因素资料进行Logistic多因素回归分析。结果　 15 6例冠状动脉造影者中 89例诊断为冠心病 (5 7.1% ) ,6 7例无冠心病(42 .9% )。Logistic多因素回归分析显示冠心病家族史、血浆总胆固醇水平及吸烟为冠心病的独立危险因素 ,其相关系数分别为 0 .6 3、0 .5 0、0 .97,优势比 (OR)分别为 1.0 6、1.6 5、2 .6 4 (P <0 .0 5 )。结论　冠心病家族史、高血浆总胆固醇水平及吸烟是青年人冠心病的发生的高危因素 ,对这类人群应尽早干预。

Risk factor analysis in youg patients with coronary artery disease

Objective To determine risk factors in patients wi th coronary artery disease (CAD) under 50 years old. Methods By cronoray angiography 156 patients with CAD under 50 years old were divided into two groups: Group 1 (n=89) with evidence of angiographic CAD and group 2 (n=67) with non-CAD as control. CAD risk factors were also collecled for logistic multivariate regression analysis. Results In 156 cases, 89 cases had angiographic CAD ( 57.1%) and 67 cases had non-CAD ( 42.9%). By multivariate logistic regression analysis, CAD family history, high-total blood cholesterol level and smoking were conformed to be independent risk factors for CAD. The old ratios (OR) were 0.63, 0.50, 0.97 (P< 0.05) and relative coefficient were 0.63, 0.50, 0.97 (P< 0.05) respectively. Conclusion CAD family history high-total blood cholesterol level and smoking were conformed to be independent risk factors in the young patients. High degree attention and proper life style control should be paid to such a group.