| Her2和Ki-67在乳腺癌中的表达和意义 |
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| 引用本文： | 钱金锋,谢慧君,蔡德巍,袁明明. Her2和Ki-67在乳腺癌中的表达和意义[J]. 中国交通医学杂志, 2011, 25(1): 28-30 |
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| 作者姓名： | 钱金锋 谢慧君 蔡德巍 袁明明 |
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| 作者单位： | 南通瑞慈医院病理科,江苏,226010 |
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| 摘 要： | 目的:研究Her2和Ki-67在乳腺癌中的表达与淋巴结转移、病理类型、组织学分级及肿瘤分期等的关系和临床意义。方法:应用免疫组织化学方法检测乳腺癌59例中Her2和Ki-67的表达,分析其与临床病理特征的关系。结果:乳腺癌59例中Her2和Ki-67的阳性表达率分别为76.3%和64.4%。两者表达在患者年龄、肿瘤大小、组织病理学类型及组织学分级之间差异无统计学意义(P>0.05);而Her2和Ki-67表达在有无淋巴结转移和肿瘤分期间差异有统计学意义(P<0.05);Her2与Ki-67表达差异有统计学意义(P<0.05)。结论:Her2和Ki-67是判断乳腺癌预后的重要指标,联合检测更有助于乳腺癌患者的临床治疗和预后判断。
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| 关 键 词： | 乳腺癌 Her2 Ki-67 免疫组织化学法 |
Expression and significance of Her2 and Ki-67 in primary breast carcinoma |
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| QIAN Jinfeng,XIE Huijun,CAI Dewei,YUAN Mingming. Expression and significance of Her2 and Ki-67 in primary breast carcinoma[J]. Chinese Medical JOurnal of Communications, 2011, 25(1): 28-30 |
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| Authors: | QIAN Jinfeng XIE Huijun CAI Dewei YUAN Mingming |
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| Affiliation: | QIAN Jinfeng,XIE Huijun,CAI Dewei,YUAN Mingming(Department of Pathology,Jiangsu Provincial Nantong RICH-Hospital,Jiangsu,226010) |
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| Abstract: | Objective:To investigate the expression of Her2 and Ki-67 in breast cancer tissues and to explore their relationship with patients' age,tumor size,lymph node metastasis,histopathological type,histology classification and the stage of cancer.Methods:The expression of Her2 and Ki-67 in 59 cases of breast cancer tissues were detected by immunohistochemistry and the clinical significance were statistically analyzed.Results:The positive expression rate of Her2 and Ki-67 in 59 cases of breast cancer tissues were ... |
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| Keywords: | Her2 Ki-67 |
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