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一叶萩碱治疗小儿脊髓灰质炎后遗症41例
引用本文:李金声,陶忠华,王聘胜,强则银,周文奎,王淑云.一叶萩碱治疗小儿脊髓灰质炎后遗症41例[J].中国新药与临床杂志,1991(6).
作者姓名:李金声  陶忠华  王聘胜  强则银  周文奎  王淑云
作者单位:河南省卫生防疫站,中国医学科学院药物研究所,周口地区防疫站,中国医学科学院药物研究所,周口地区防疫站,中国医学科学院药物研究所 郑州 450003
摘    要:本文报告一叶萩碱治疗脊髓灰质炎后遗症41例(男30例,女11例,平均2.0±0.6yr),有效者32例,有效率78%。23例肌肉注射0.8mg/(kg·d),qd,14d为一个疗程,共3个疗程;18例穴位注射0.6mg/(kg·d),qd,疗程同上。疗效基本相同,但肌肉注射患者痛苦小、方法简单、宜作首选。增加疗程可以提高疗效,以坚持较长疗程治疗为宜。

关 键 词:一叶萩碱/治疗应用  脊髓灰质炎  肌萎缩  中草药

Treatment of sequelae of poliomyelitis with securinine in 41 children
LI Jin-Sheng,TAG Zhong-Hua,WANG Pin-Sheng,QIANG Ze-Yin,ZHOU Wen-Kui,WANG Shu-Yun.Treatment of sequelae of poliomyelitis with securinine in 41 children[J].Chinese Journal of New Drugs and Clinical Remedies,1991(6).
Authors:LI Jin-Sheng  TAG Zhong-Hua  WANG Pin-Sheng  QIANG Ze-Yin  ZHOU Wen-Kui  WANG Shu-Yun
Abstract:From 1983-1988, securinine was given to 41 children (M 30, F 11; age 2.0 0.6 yr) with the sequelae of poliomyelits, among them 32 children were effective, the response rate was 78%. Intramuscular injection 0.8 mg/(kg.d), qd or acupuncture point injection 0.6 mg/(kg.d), qd was applied, 14 d as a course for 3 courses with the same efficacy. Intramuscular injection is preferable as it was easy to apply and caused less pain. It is advisable to have a longer period of treatment.
Keywords:securinine/therapeutic use  poliomyelitis  muscular atrophy  Chinese herbal drugs
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