应用Nexgen LPS-Flex人工膝关节置换治疗重度膝关节退行性骨关节病126例的早期效果

背景：以往膝关节置换后患者不能获得高度屈曲度，这与假体及患者因素有关。目的：观察为膝关节高度屈曲而设计的Nexgen-LPS-Flex人工膝关节置换治疗重度膝关节退行性骨关节病的早期疗效。方法：回顾性分析重度退行性膝关节骨关节病126例(173膝)接受Zimmer 高屈曲后稳定(Nexgen-LPS-Flex)人工膝关节置换的相关数据。结果与结论：126例173个膝关节置换时间为(78.2±13.5)min。股胫角为外翻5°~7°，关节活动范围置换前为(78.4±10.6)°，置换后为(112.8±18.6)°。置换前HSS评分为(32.4±12.0)分，出院时为(87.9±10.9)分(P < 0.01)。4例(4膝)切口愈合障碍；确诊下肢深静脉血栓3例，均行介入治疗康复出院；1例出现伸膝滞缺，无神经血管损伤发生，无感染、骨折、假体松动、脱位等并发症。结果表明，Nexgen LPS-Flex人工膝关节置换治疗重度膝关节退行性骨关节病早期未发现有骨溶解、假体松动及衬垫严重磨损等并发症。

Early-stage effect of Nexgen-LPS-Flex prosthesis on severe knee degenerative joint disease in 126 cases

BACKGROUND: In the past, patients cannot had high flexion after total knee arthropalsty as the aspect of prosthesis and rehabilitation. OBJECTIVE: To investigate the preliminary clinical outcome of NexGen LPS-Flex system in severe knee degenerative joint diseases. METHODS: 126 patients (173 knees) with severe knee degenerative joint disease underwent primary total knee arthroplasty with NexGen LPS-Flex prostheses. Clinical results were evaluated preoperatively and postoperatively. RESULTS AND CONCLUSION: The average operation time was (78.2±13.5) minutes. Femorotibial angle was evaginated 5°-7°. The range of motion was (78.4±10.6)° and (112.8±18.6)° prior to and after replacement. The HSS score was (32.4±12.0) points before replacement and (87.9±10.9) points at discharge (P < 0.01). Four cases (4 knees) had a wound healing disorder, 3 patients had deep venous thrombosis and cured after intervention therapy, and 1 patient presented with extension disorder. No osteolysis, loosening and severe friction happened. The results indicated that there were no complications at early stage of Nexgen-LPS-Flex prosthesis for severe knee degenerative joint diseases.