电针对清醒狗肾水、钠、钾排出的影响

<正> 许多临床与实验工作表明,针刺穴位可以使急性肾炎与慢性肾炎患者排尿量显著增加,全身体表浮肿消退或减轻。针刺对水负荷人体、慢性输尿管瘘狗、以及盐水负荷实验动物也有显著的利尿或利尿排钠作用。但其针刺作用机制尚未完全阐明。近年来报道:针刺对高血压患者有降压效应,对低血压休克患者有升压效应,但对正常人和正常动物的血压则无明显的影响,表明针刺对机体动脉血压水平有调整作用。针刺对肾泌尿功能的影响是否也具有调整作用,本工作对下列二个问题进行探讨:(1)电针能促进盐水负荷动物的肾水钠排出,但对正常无盐水负荷动物的肾水钠排出是否也有效?(2)电针促进盐水负荷狗肾水钠排出时,对尿钾的排出是否也有效?为了避免药物麻醉对实验动物针刺效应的影响,本工作在清醒慢性输尿管瘘狗进行研究。

Effect of electroacupuncture on the urine flow, sodium excretion and potassium excretion in the conscious dog

Unanesthetized dogs with chronic ureteral and gastric fistulae were infused with 0.8% NaCl solution into the stomach at a constant rate for maintaining a state of saline loading. In these animals, there was a steady renal excretion of water, sodium and potassium. However, after a 20-minute unilateral electroacupuncture of the points corresponding to "Sanyinjao" and "Zhaohai" in human leg as described in Traditional Chinese Medicine caused a marked increase in urine flow and urinary sodium excretion, but had no significant effect on urinary potassium excretion. In another group of normal unanesthetized dogs (without saline loading), the effect of electroacupuncture mentioned above no longer appeared. Owing to the facts that electroacupuncture merely increased the water and sodium excretion of kidneys in saline-loading unanesthetized dogs, and had no effect in normal unanesthetized dogs, it is concluded that the effects of electroacupuncture on the urine flow and sodium excretion in saline-loading unanesthetized dogs is an action of normalization by acupuncture.