肿瘤特异性生长因子在恶性肿瘤诊断及治疗中的临床意义

目的：探讨肿瘤特异性生长因子（TSGF）诊断肿瘤的特异性、化疗前后的变化及临床意义。方法：采用福建新大陆生物技术公司提供的TSGF癌症快速检测试剂盒，对临床诊断为良性肿瘤的50例患者、恶性肿瘤155例患者及部分治疗后患者血清中的TSGF含量进行检测和比较。结果：⑴恶性肿瘤患者血清中TSGF含量明显高于良性肿瘤，敏感性为78.71%，特异性为92.00%，准确性为81.95%。⑵治疗后病情好转的病人血清中TSGF含量明显下降。结论：TSGF检测对恶性肿瘤的诊断、疗效观察、病情监测有重要意义。

The clinical significance of tumor specific growth factor in diagnosis and treatment of malignant tumor

Objective: To study the specificity of tumor specific growth factor (TSGF) in diagnosis of cancer,in the changes before and after chemotherapy and the clinical value. Methods: With the TSGF quick cancer diagnostic reagent Kit produced by Fujian New Land, the TSGF level was measured in 50 patients with benign tumor,155 cases with malignant tumor and a part of patients after chemotherapy. Results: (1) The positive rate of TSGF of malignant tumor was 78.71%,the sensitivity was 84.7%,specificity was 92.0% and the accuracy was 81.95%.(2)The serum TSGF level decreased remarkably in the patients who took a favourable turn after treatment. Conclusion: TSGF can take an important role in the diagnosis of tumor,observing efficacy of treatment and monitoring course of the disease.