| 双嘧达莫对小鼠免疫功能的影响 |
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| 引用本文： | 冯垄熙,朱宝明,陈军军,曾召录. 双嘧达莫对小鼠免疫功能的影响[J]. 中国药理学通报, 1995, 0(6) |
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| 作者姓名： | 冯垄熙 朱宝明 陈军军 曾召录 |
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| 作者单位： | 兰州军区后勤部军事医学研究所 |
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| 摘 要： | 双嘧达莫Ｄｉｐ１，１０，４０ｍｇ·ｋｇ－１降低小鼠脾脏系数和末梢血白细胞数，抑制全血白细胞和腹腔巨噬细胞的吞噬功能。降低小鼠血清溶菌酶的含量和血清溶血素的生成，抑制空斑形成细胞的溶血能力。
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| 关 键 词： | 双嘧达莫；溶菌酶；溶血素；空斑形成细胞；吞噬作用 |
Effects of dipyridamole on murine immunity |
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| FENG Yan-Xi,ZHU Bao-Min,CHENG Jun-Jun,ZEN Zhao-Lu. Effects of dipyridamole on murine immunity[J]. Chinese Pharmacological Bulletin, 1995, 0(6) |
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| Authors: | FENG Yan-Xi ZHU Bao-Min CHENG Jun-Jun ZEN Zhao-Lu |
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| Affiliation: | Institute of Military Medical Sciences of Lanzhou PLA Lanzhou 730020 |
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| Abstract: | Dipyridamole(Dip)1,10,40 mg·kg-1 ip decreased murine spleen index and peripheral white blood cell number,inhibited the ability of peripheral white blood cells and peritoneal macrophages phagocytosing Staphylococcus albus of[3H]TdR incorporation in mice.inbibited production of antibody in mice immunized by SRBC and declined hemolytic ability of plaque forming cells in mice.Dip 1,10 mg·kg-1 decreased murine serum lysozyme concentration.Resluts suggest that dipyridamole plays an important role in murine immunity. |
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| Keywords: | dipyridamole lysozyme hemolysin plaque forming cells phagocytosing |
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