| 一例快速异常血红蛋白—Hb J Lome(β59(E3)Lys→Asn)的一级结构分析 |
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| 引用本文： | 陶重仪,李西兴,张玲叶.一例快速异常血红蛋白—Hb J Lome(β59(E3)Lys→Asn)的一级结构分析[J].新乡医学院学报,1987(3). |
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| 作者姓名： | 陶重仪 李西兴 张玲叶 |
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| 作者单位： | 新乡医学院生物化学教研室，新乡医学院生物化学教研室，新乡医学院生物化学教研室 |
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| 摘 要： | 本文报告在河南省封丘县发现的一例快速异常血红蛋白,患者为13岁男孩,汉族。本例变异血红蛋白电泳迁移率属J组血红蛋白,其含量占血红蛋白总量的51.4％,没有临床表现者占17％,异丙醇试验阴性。一级结构分析结果显示本例变异血红蛋白是Hb J Lome(β59(E3)Lys→Asn)。这种变异血红蛋白在河南省是第一次发现。
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| 关 键 词： | 指纹图谱 肽链裂解 肽斑 氨基酸顺序分析 |
primary structural analysis of a fast moving variant hemoglobin—Hb Lome(β59(E3)Lys→Asn)found in Henan. |
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| Tao Zhong-Yi,Li Xi--Xin Zhang Ling Yi.primary structural analysis of a fast moving variant hemoglobin—Hb Lome(β59(E3)Lys→Asn)found in Henan.[J].Journal of Xinxiang Medical College,1987(3). |
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| Authors: | Tao Zhong-Yi Li Xi--Xin Zhang Ling Yi |
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| Institution: | Tao Zhong-Yi;Li Xi--Xin Zhang Ling Yi Department of Biochemistry Xin xiang medical college |
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| Abstract: | This paper describes a fast moving variant hemoglobin found in a 13 years old boy of Han ethnic group living in Feng Qiu c- ounty,Henan Province.This var- iant,had an electro-Phoretic mobil- ity of the J type hemoglobin and amounted to 51.4% of the total he- moglobin.No clinical manifestati- ons were observed.17%Isopropan- ol Precipitation test of the carrie was negative. Result of primary strctural an- alysis showed that the variant hem- oglobin in Hb J Lome (β59(E3)Lys →Asn).This variant hemoglobin w- as first found in Henan province. |
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| Keywords: | Fingerprint Peptide chain cleavage Peptide mapping Amillo-acid sequence analysis |
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