| C-erbB-2、ER、PR在乳腺浸润性导管癌中的表达及意义 |
| |
| 引用本文： | 张喜凤,赵红兵,李惠翔. C-erbB-2、ER、PR在乳腺浸润性导管癌中的表达及意义[J]. 中国妇幼保健, 2010, 25(7) |
| |
| 作者姓名： | 张喜凤 赵红兵 李惠翔 |
| |
| 作者单位： | 1. 商丘医学高等专科学校病理学教研室,河南,商丘,476100
2. 郑州大学第一临床医院 |
| |
| 摘 要： | 目的:探讨乳腺浸润性导管癌中ER、PR和C-erbB-2的表达,并分析其相关性。方法:应用免疫组化方法,检测60例乳腺浸润性导管癌患者中ER、PR和C-erbB-2的表达情况。结果:ER、PR和C-erbB-2的阳性表达率分别为58.3%(35/60)、41.7%(25/60)和40.0%(24/60);ER与PR表达之间差异有统计学意义(P0.05);ER与C-erbB-2表达之间差异无统计学意义(P0.05);PR与C-erbB-2表达之间差异无统计学意义(P0.05)。结论:C-erbB-2和ER、PR可能是乳腺癌预后指标的独立因子,但C-erbB-2表达与ER、PR关系有待研究。ER、PR在乳腺癌中的表达有相关性。
|
| 关 键 词： | 乳腺癌 C-erbB-2 雌激素受体 孕激素受体 |
Expression levels and significance of C-erbB-2,ER and PR in patients with invasive breast ductal carcinoma |
| |
| ZHANG Xi-Feng,ZHAO Hong-Bing,LI Hui-Xiang. Expression levels and significance of C-erbB-2,ER and PR in patients with invasive breast ductal carcinoma[J]. Maternal and Child Health Care of China, 2010, 25(7) |
| |
| Authors: | ZHANG Xi-Feng ZHAO Hong-Bing LI Hui-Xiang |
| |
| Affiliation: | ZHANG Xi-Feng,ZHAO Hong-Bing,LI Hui-Xiang.Staff Room of Pathology,Shangqiu Medical College,Shangqiu 476100,Henan,China |
| |
| Abstract: | Objective:To explore the expression levels and correlation of estrogen receptor(ER),progestogen receptor(PR) and C-erbB-2 in patients with invasive breast ductal carcinoma.Methods:The expression levels of ER,PR and C-erbB-2 in 60 patients with invasive breast ductal carcinoma were detected by immunohistochemical method.Results:The positive expression rates of ER,PR and C-erbB-2 were 58.3 %(35/60),41.7 %(25/60) and 40.0%(24/60),respectively.There was significant difference between ER and PR(P<0.05).There was... |
| |
| Keywords: | Breast carcinoma C-erbB-2 Estrogen receptor Progestogen receptor |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
