| 血清总胆固醇与冠心病痰瘀证候关系Meta分析 |
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| 引用本文： | 喻松仁,周丽,程绍民,袁肇凯.血清总胆固醇与冠心病痰瘀证候关系Meta分析[J].世界科学技术,2013(6):1383-1387. |
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| 作者姓名： | 喻松仁 周丽 程绍民 袁肇凯 |
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| 作者单位： | [1]湖南中医药大学基础医学院,长沙410007 [2]江西中医药大学基础医学院,南昌330004 [3]江西中医药大学计算机学院,南昌330004 |
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| 基金项目： | 教育部高校博士点基金项目（优先发展领域）（20124323130001）：冠心病血瘀证心肌细胞能量代谢网络模型的研究,负责人：袁肇凯; 国家自然科学基金委面上项目（81273670）：冠心病血瘀证心肌细胞能量代谢网络模型的研究,负责人：袁肇凯; 江西省卫生厅中医药科研计划（2012A060）：动脉粥样硬化“痰瘀”演变的内在机制研究,负责人：喻松仁 |
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| 摘 要： | 目的：探讨血清总胆固醇（TC）的异常改变与冠心病痰瘀证候的关系。方法：应用Meta分析法对10篇文献中冠心病＂痰浊证＂、＂血瘀证＂患者与＂正常对照者＂的TC含量进行综合分析。结果：TC含量显示,血瘀证患者比正常对照者标准差高0.99~2.426倍,Total合并=0.71,Total合并95%置信区间为0.16~1.25;痰浊证患者比正常对照者标准差高1.019~3.761倍,Total合并=1.05,Total合并95%置信区间为0.43~1.68。结论 ：冠心病患者血瘀证和痰浊证的TC含量与正常对照者比较存在显著差异,TC含量的异常改变可作为冠心病痰瘀辨证的客观指标之一。
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| 关 键 词： | 冠心病 证候 血清总胆固醇 Meta分析 |
Meta-analysis on Relationship between Serum Total Cholesterol and Coronary Heart Disease of Phlegm and Blood Stasis Syndrome |
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| Yu Songren,Zhou Li,Cheng Shaomin,Yuan Zhaokai.Meta-analysis on Relationship between Serum Total Cholesterol and Coronary Heart Disease of Phlegm and Blood Stasis Syndrome[J].World Science and Technology(Modernization of Traditional Chinese Medicine),2013(6):1383-1387. |
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| Authors: | Yu Songren Zhou Li Cheng Shaomin Yuan Zhaokai |
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| Institution: | 1. School of Preclinical Medicine, Hunan University of Traditional Chinese Medicine, Changsha 410007, China; 2. School of Preclinical Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China; 3. School of Computer, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China) |
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| Abstract: | This study was aimed to find out the relationship between the serum total cholesterol （ TC ） and coronary heart disease （ CHD ） of phlegm and blood stasis syndrome . Meta -analysis was used on the comprehensive analysis of ten research literatures on TC content of CHD patients with ＂phlegm-turbid syndrome＂, ＂blood-stasis syndrome＂ and ＂normal control .＂ The results showed that the content of TC was 0.99-2.426 times h igher standard deviation in the blood-stasis syndrome patients than in the normal control, Totalcombined = 0.71. And the 95% confidence intervals of Totalcombined was 0.16-1.25. And the content of TC was 1.019-3.761 times higher standard deviation in the phlegm-turbid syndrome than in the normal control, Totalcombined= 1 . 05 . And the 95% confidence intervals of Totalcombined was 0 . 43-1 . 68 . It was concluded that there were significant variations of TC content in CHD patients with blood-stasis and phlegm-turbid syndrome compared to normal control . Therefore , abnormal changes of TC content can be used as one of the objective CHD diagnostic criteria of phlegm and blood stasis syndrome . |
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| Keywords: | Coronary heart disease syndrome serum total cholesterol meta-analysis |
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