| 旋毛虫成虫可溶性抗原免疫小鼠T淋巴细胞亚群的动态变化 |
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| 引用本文： | 申丽洁,罗志勇,朱声华.旋毛虫成虫可溶性抗原免疫小鼠T淋巴细胞亚群的动态变化[J].中国人兽共患病杂志,2002,18(5):78-80. |
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| 作者姓名： | 申丽洁 罗志勇 朱声华 |
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| 作者单位： | 大理医学院寄生虫学教研室,大理医学院临床医学系
,华西医科大学寄生虫学教研室 云南,671000 |
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| 摘 要： | 目的 观察旋毛虫成虫可溶性抗原免疫小鼠T淋巴细胞亚群的动态变化。方法采用流式细胞术分别检测旋毛虫感染后 7、14、2 1、2 8、35天小鼠外周血CD+ 4 、CD+ 8T淋巴细胞的百分率。结果 免疫小鼠CD+ 4 、CD+ 8细胞增加 ,CD+ 4 /CD+ 8细胞比值与正常组比较无明显差异。结论 旋毛虫成虫可溶性抗原免疫小鼠未出现免疫抑制现象
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| 关 键 词： | 旋毛虫 抗原 CD+4细胞 CD+8细胞 |
| 文章编号： | 1002-2694(2002)05-0078-03 |
| 收稿时间： | 2002-05-20 |
Dynamic changes of T lymphocytes subsets in Trichinella spiralis AWAg immune mice |
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| Shen Lijie Luo Zhiyong Zhu Shenghua.Dynamic changes of T lymphocytes subsets in Trichinella spiralis AWAg immune mice[J].Chinese Journal of Zoonoses,2002,18(5):78-80. |
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| Authors: | Shen Lijie Luo Zhiyong Zhu Shenghua |
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| Institution: | Shen Lijie Luo Zhiyong Zhu Shenghua |
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| Abstract: | Objective To observe dynamic changes of T lymphocyte subsets in Trichinella spiralis adult worm soluble antigens (AWAg) immune mice Methods The percentage of CD 4 and CD 8 T cells were examined by flow cyteometry on 7,14,21,28,35 days after mice infected with Trichinella spiralis respectively Results CD 4 and CD 8 T cells of immune mice increased,the ratio of CD 4/CD 8 cells was no difference comparing with normal mice Conclusions The immune function of AWAg immune mice was no inhibited |
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| Keywords: | Trichinella spiralis antigen CD 4 cell CD8 cell |
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