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Central monoamines and antinociceptive drug action
Authors:B.-D. Gö  rlitzH.-H. Frey
Affiliation:Dept. of Pharmacology and Toxicology, School of Veterinary Medicine, Free University, Berlin, Germany
Abstract:Experiments were perfomed in rats to elucidate the role of central 5-HT and catecholamines in the mediation of the antinociceptive effects of d-amphetamine, d-p-chloroamphetamine, morphine and aminopyrine. The method of Randall and Selitto (1957) was used for determining the antinociceptive effect.
Keywords:Antinociceptive action   d-p-Cloroamphetamine   Morphine   Central Monoamines   d-Amphetamine   Aminopyrine
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