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随行生理监护系统设计及性能初步验证
引用本文:曹德森,李德玉,张政波,刘晓莉,梁洪,贺茂庆,俞梦孙. 随行生理监护系统设计及性能初步验证[J]. 生物医学工程学杂志, 2019, 0(1): 121-130
作者姓名:曹德森  李德玉  张政波  刘晓莉  梁洪  贺茂庆  俞梦孙
作者单位:北京航空航天大学生物与医学工程学院;解放军总医院医学工程保障中心;北京海思瑞格科技有限公司;空军航空医学研究所
基金项目:国家自然科学基金面上项目(61471398);首长保健专项(16BJZ23);解放军总医院院企合作项目(YQ-ZZB-201501);解放军总医院苗圃基金(16KMM54;16KMM53);医药协同科技创新研究(Z181100001918023);赛尔网络下一代互联网技术创新项目(NGII20160701)
摘    要:为实现住院患者连续生命体征监测,研制了随行生理参数监护系统SensEcho。该系统由随行生理参数监测终端、无线组网和数据传输单元、中央监护系统三部分组成。其中随行生理参数监测终端为一件柔性背心,内嵌有呼吸感应体积描记传感器和织物心电电极,实现心电、呼吸、体位和体动等基本生理参数的穿戴式低负荷监测;无线生理信号传输单元为基于WiFi技术的组网系统,能够实现病区内多个患者的移动监护,并设计有多重数据续传和数据完整性保障机制;中央监护系统实现所有随行生理参数监测终端数据的显示和患者集中管理,设计有后台数据服务器和算法服务器,支持医疗大数据深度挖掘分析应用。为验证系统性能,我们开展了生理参数检测算法有效性和受试者可靠性测试,以及无线组网和数据传输可靠性测试。测试结果显示,系统无论在基本生理参数监测还是无线数据传输方面都能达到可靠性要求。该系统在医疗领域的应用有望开启个体化连续生命体征监护医疗新模式,为疾病诊断提供基于连续动态生理数据分析的精准信息。

关 键 词:可穿戴  心肺生理参数  无线  中央监测  住院患者

Design and preliminary validation of a ubiquitous and wearable physiological monitoring system
CAO Desen,LI Deyu,ZHANG Zhengbo,LIU Xiaoli,LIANG Hong,HE Maoqing,YU Mengsun. Design and preliminary validation of a ubiquitous and wearable physiological monitoring system[J]. Journal of biomedical engineering, 2019, 0(1): 121-130
Authors:CAO Desen  LI Deyu  ZHANG Zhengbo  LIU Xiaoli  LIANG Hong  HE Maoqing  YU Mengsun
Affiliation:(School of Biological Science and Medical Engineering,Beihang University,Beijing 100191,P.R.China;Department of Biomedical Engineering,Chinese PLA General Hospital,Beijing 100853,P.R.China;Beijing SensEcho Science &Technology Co.,Ltd,Beijing 100041,P.R.China;Institute of Aviation Medicine Beijing 100037,P.R.China)
Abstract:To achieve continuously physiological monitoring on hospital inpatients,a ubiquitous and wearable physiological monitoring system SensEcho was developed.The whole system consists of three parts:a wearable physiological monitoring unit,a wireless network and communication unit and a central monitoring system.The wearable physiological monitoring unit is an elastic shirt with respiratory inductive plethysmography sensor and textile electrocardiogram(ECG) electrodes embedded in,to collect physiological signals of ECG,respiration and posture/activity continuously and ubiquitously.The wireless network and communication unit is based on WiFi networking technology to transmit data from each physiological monitoring unit to the central monitoring system.A protocol of multiple data retransmission and data integrity verification was implemented to reduce packet dropouts during the wireless communication.The central monitoring system displays data collected by the wearable system from each inpatient and monitors the status of each patient.An architecture of data server and algorithm server was established,supporting further data mining and analysis for big medical data.The performance of the whole system was validated.Three kinds of tests were conducted:validation of physiological monitoring algorithms,reliability of the monitoring system on volunteers,and reliability of data transmission.The results show that the whole system can achieve good performance in both physiological monitoring and wireless data transmission.The application of this system in clinical settings has the potential to establish a new model for individualized hospital inpatients monitoring,and provide more precision medicine to the patients with information derived from the continuously collected physiological parameters.
Keywords:wearable  cardiopulmonary physiologic monitoring  wireless  central monitoring  hospital inpatient
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