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脐血血清对正常及白血病骨髓粒-单祖细胞生长的影响
引用本文:王建宁,陈玉心,敖忠芳,盛瑞兰. 脐血血清对正常及白血病骨髓粒-单祖细胞生长的影响[J]. 南京医科大学学报(自然科学版), 1994, 0(4)
作者姓名:王建宁  陈玉心  敖忠芳  盛瑞兰
作者单位:南京海军医院
摘    要:利用粒-单祖细胞集落(CFU-GM)的体外培养,观察脐血血清(UCS)对正常及白血病骨髓造血祖细胞生长的影响,结果表明:UCS对正常及急性白血病(AL)患者完全缓解的骨髓CFU-GM形成有一定增殖作用,而对初发/复发未治AL患者的骨髓CFU-GM形成无类似作用。

关 键 词:脐血血清;粒-单祖细胞集落形成单位;急性白血病;造血生长因子

Influence of Umbilical Cord Serum on Growth of Normal and Leukemic Myeloid Puogenitor Cells
Wang Jianning,et al.. Influence of Umbilical Cord Serum on Growth of Normal and Leukemic Myeloid Puogenitor Cells[J]. Acta Universitatis Medicinalis Nanjing, 1994, 0(4)
Authors:Wang Jianning  et al.
Affiliation:Wang Jianning, et al.
Abstract:In the present study, semi-solid crltured normal and leukmic marrow cells were treated with different umbilicsl cord serum (UCS) concentrations and the effects were evaluted using the assay of CFU-GM in vitro.The data indicate that UCS enhances myeloid hemopoiesis in marrow cells of normal persons and patients with AL-CR, but it has no influence on growth of CFU-GM in patients untreated or relapsed.
Keywords:umbilical cord serum  acute leukemia  granulocyte-macrophage   colony formation units  hemopoietic growth factors
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