Impact of hypoxic hepatitis on mortality in the intensive care unit |
| |
| Authors: | Valentin Fuhrmann Nikolaus Kneidinger Harald Herkner Gottfried Heinz Mariam Nikfardjam Anja Bojic Peter Schellongowski Bernhard Angermayr Maximilian Sch?niger-Hekele Christian Madl Peter Schenk |
| |
| Affiliation: | Intensive Care Unit 13H1, Department of Gastroenterology and Hepatology, Internal Medicine 3, Medical University of Vienna, W?hringer Gürtel 18-20, 1090 Vienna, Austria. valentin.fuhrmann@meduniwien.ac.at |
| |
| Abstract: | Purpose Hypoxic hepatitis (HH) is a form of hepatic injury following arterial hypoxemia, ischemia, and passive congestion of the liver. We investigated the incidence and the prognostic implications of HH in the medical intensive care unit (ICU). Methods A total of 1,066 consecutive ICU admissions at three medical ICUs of a university hospital were included in this prospective cohort study. All patients were screened prospectively for the presence of HH according to established criteria. Independent risk factors of mortality in this cohort of critically ill patients were identified by a multivariate Poisson regression model. Results A total of 118 admissions (11%) had HH during their ICU stay. These patients had different baseline characteristics, longer median ICU stay (8 vs. 6?days, p?p?p?p?p?=?0.359). Conclusions Hypoxic hepatitis (HH) occurs frequently in the medical ICU. The presence of HH is a strong risk factor for mortality in the ICU in patients requiring vasopressor therapy. |
| |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
