静注潘生丁,锝—甲氧异丁异睛心肌灌注SPECT诊断冠心病的评价

目的:全面评价静注潘生丁99m锝—MIBI心肌单光子发射计算机断层显像术(SPECT)诊断冠心病(CAD)的临床价值.材料和方法:在51名受试者中与冠状动脉造影比较得出SPECT的敏感性、特异性、准确度、阳性预测值、阴性预测值;并将SPECT与活动平板心电图(TECG)、Holter直接比较.结果:SPECT的敏感性为83%、特异性84%、准确度84%、阳性预测值89%、阴性预测值86%;在均接受SPECT、TECG的31例中,前者较后者为优(敏感性89%与68%、特异性77%与54%、准确度84%与62%).在42名受试者中SPECT也较Holter准确(敏感性80%与48%、特异性82%与47%、准确度81%与48%).结论:SPECT心肌灌注显像是准确性较高的诊断CAD的无创伤性方法.

Evaluation of Intravenous Dipyridamole 99mTc-MIBMyocardial Perfusion by SPECT in Diagnosing Coronary Heart Disease

Purpose: Intravenous dipyridamole 99mTc - MIBI myocardial perfusion by single photon e-mission computer tomography(SPECT) was evaluated for its diagnostic value in coronary heartdisease(CAD). Material and Methods: By means of comparison with coronary arterioga-rphy, SPECT's sensitivity, specificity, accuracy rate, positive predictive value, negative predictivevalue were obtained; and SPECT was compared directly with treadmill exercise electrocardiog-raphy(TECG) and Holter. Results: SPECT's sensitivity reached to 83%, specificity 84%, ac-curacy rate 84%, positive predictive value 89%, negative predictive value 86%; In 31 re-ceivers who experienced SPECT and TECG,SPECT was superior to TECG in sensitivity(89%vs. 68% ), specificity(77%vs. 54% ), accuracy rate(84%vs. 62% ); In another 42 receiversSPECT also possessed higher accuracy than Holter in sensitivity(80%vs. 48% ), specificity(82%vs. 47% ), accuracy rate(81 %vs. 48% ); Conclusion: SPECT is a highly accuratemethod for diagnosing CAD.