Challenges in the mid and the lower face

The cosmetic use of botulinum toxin in the mid and lower third of the face has some challenges that must be overcome with experience. This paper briefly reviews the application of botulinum toxin in these regions. The treatment of the mid and lower face with botulinum toxin should be carried out with low doses. When starting with this technique, it is advisable to do a two‐step treatment especially for those not acquainted with these regions.