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黑加仑油药理作用研究
引用本文:周效平,李庆忠,马辉.黑加仑油药理作用研究[J].中医药学报,2002,30(3):56-57.
作者姓名:周效平  李庆忠  马辉
作者单位:黑龙江省药品检验所,黑龙江,哈尔滨,150001
摘    要:对黑加仑油的降血脂作用进行探讨。实验结果表明 ,对家兔实验性高脂血症 ,黑加仑油口服 0 3g/kg ,能降低TC、TG ;口服 0 1 4g/kg ,能降低LDL -C ,对HDL -C作用不明显。同时该剂量对家兔动脉粥样硬化有明显的抑制作用。其作用机理 ,与黑加仑中含有大量γ -亚麻酸有关。

关 键 词:黑加仑油  降血脂  药理实验
文章编号:1002-2392(2002)03-0056-02

Study of The Fuction of Ribes Nigrum L Seed Oil
Zhou Xiaoping,Li Qingzhong,MaHui Hei Longjiang Provincial Institute for Drug Control,Harbin.Study of The Fuction of Ribes Nigrum L Seed Oil[J].Acta Chinese Medicine and Pharmacology,2002,30(3):56-57.
Authors:Zhou Xiaoping  Li Qingzhong  MaHui Hei Longjiang Provincial Institute for Drug Control  Harbin
Institution:Zhou Xiaoping,Li Qingzhong,MaHui Hei Longjiang Provincial Institute for Drug Control,Harbin 150001
Abstract:Ribes nigrum L seed oil was abstracted from the seed of riibes nigrum L,which contained many kinds of unsaturated fatty acids.The rabbits treated with the dose of 0 3g/kg and 0 14g/kg which suffered from an experimental hyperlipemia.The results siginified the serum TC and TG of the rabbits was reduced by the dose of 0 3g/kg. And the level of LDL-c was decreased but the HDL-c was not obiviously changed by the dose of 0 14g/kg. Moreover,the dose of 0 14g/kg had the evident inhibition effect on atherosclerosis of rabbits.The action mechanism of ribes nigrum Lseed oil may be related to r lionlenic acid contained in it.
Keywords:ribes nigrum L seed oil  pharmacological experiment  lipid  reducing  
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