人工耳蜗植入术后神经反应遥测技术的参数设置

澳大利亚 Cochlear公司的 Nucleus2 4型多导人工耳蜗系统首次提供了直接测量电诱发听神经复合动作电位 (electrically evoked compound action potential,ECAP)的技术手段——神经反应遥测 (neural response telemetry,NRT)技术。本文对 2 0例 Nucleus2 4型多导人工耳蜗植入患者进行 NRT反应波形采集 ,选取反应波形较清晰的电极作为测试电极。每次只改变一个测试参数 ,观察波形的变化 ,总结出不同测试参数的改变对波形造成的影响。其中对波形影响较大的有电流强度 (current level,CL) ,刺激脉宽 (stimulation pulse width)、延迟时间 (delay)、增益 (gain)、掩蔽刺激间期 (masker advance)等。对波形采集时间影响显著的是刺激速率和叠加次数。在此基础上设计出优化的参数调整顺序 ,用于快速采集反应波形 ,提高临床工作效率

The optimal designing of parameters for neural response telemetry

ABSTRACT Neural response telemetry (NRT)is a method that enables direct measurements of the electrically evoked compound action potential (ECAP) of the auditory nerve of cochlear implant patients using Nucleus C124M cochlear implant system.In this project,twenty patients who were implanted with Nucleus C124 M underwent measurements of the ECAP using the NRT system .It was expect to observe the changes of the responses by changing the parameters in the NRT 2 04 software.It is concluded that the parameters that make great influences to the response waves are CL (current level ),stimulation pulse width,gain,delay and masker advance.The parameters that make great influences to the record time are stimulation rate and number of sweeps.The main parameters that need to be changed in the measurement are CL,delay,gain and stimulation rate.In order to reliably and quickly record the ECAP responses from cochlear implant recipients,a specific protocol is proposed for the measurement.