750例健康儿童心率变异性分析

Objective To investigate the range of normal values of heart rate variability (HRV) in 750 healthy children,and to explore the relationship between the value of HRV and age. Methods A total 750 healthy children were randomly divided into six groups according to their ages as follows: group Ⅰ ( less 1 month), group Ⅱ ( 1 month to 1 years old), group Ⅲ ( 1 to 3 years old), group Ⅳ (3 to 6 years old), group Ⅴ (6 to 11 years old)and group Ⅵ( 11 to 16 years old). HRV time domain value(SDNN、SDANN、PNN50、rMSSD)and spectral power value( TF、VLF、LF、 HF、LF/HF)were measured by 24 dynamic electrocardiogram in all children. Results (1)The HRV time domain values( SDNN 、SDANN、rMSSD)were increased with age, there were significant differences among six groups ( P ＜ 0.05 and P ＜ 0. 01 ). ( 2 ) The spectral power values ( TF、VLF、LF、HF) comparison showed significant differences among six groups( P ＜0. 05 and P ＜0. 01 ). Conclusion HRV varies significantly with age, and it increases with age in children. The values generated in this study may be useful in determining abnormal ranges of HRV.

Heart rate variability in 750 healthy children with aging