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慢性化脓性中耳炎胆固醇肉芽肿6例临床观察
引用本文:方玲,张天宇,吴俐雯.慢性化脓性中耳炎胆固醇肉芽肿6例临床观察[J].临床耳鼻咽喉头颈外科杂志,2001,15(2):64-65.
作者姓名:方玲  张天宇  吴俐雯
作者单位:上海医科大学附属眼耳鼻咽喉科医院耳鼻咽喉科(
摘    要:目的 :探讨慢性化脓性中耳炎胆固醇肉芽肿的发病机制 ,临床及影像学的诊断与鉴别。方法 :对 6例经手术和病理证实的、继发于慢性化脓性中耳炎的胆固醇肉芽肿患者的病例资料进行分析。结果 :胆固醇肉芽肿可与多种中耳疾病同时存在 ,MRI检查 T1 W与 T2 W皆为高信号。结论 :胆固醇肉芽肿的发病机制为中耳的其它疾病如胆脂瘤、硬化灶等导致的通气受阻 ,仅凭 CT及临床体征不能区别胆固醇肉芽肿与胆脂瘤 ,MRI对本病诊断有极大的价值。

关 键 词:胆固醇肉芽肿  化脓性中耳炎  听力障碍
文章编号:1001-1781(2001)02-0064-02
修稿时间:2000年5月14日

A clinical analysis of cholesterol granuloma following chronic suppurative otitis media
FANG Lin,ZHANG Tianyu,Wu Liwen.A clinical analysis of cholesterol granuloma following chronic suppurative otitis media[J].Journal of Clinical Otorhinolaryngology,2001,15(2):64-65.
Authors:FANG Lin  ZHANG Tianyu  Wu Liwen
Institution:Department of Otorhinolaryngology, EENT Hospital, Shanghai Medical University, Shanghai 200031.
Abstract:Objective:To investigate the pathophysiological mechanism,clinical menifestation and radiographic diagnosis of cholesterol granuloma following chronic supperative otitis media.Method:Six cases of CG following chronic suppurative otitis media, confirmed by surgery and pathology,were reviewed and analyzed.Result:CG frequently accompanied with other middle ear diseases,and was shown as a high signal intensity on both T1 and T2 weighted images in magnetic resonance imaging(MRI).Conclusion:It was postulated that the obstruction of pneumatized temporal bone air cells,caused by other middle ear diseases such as cholesteatoma and tympanosclerosis,might be the pathophsiological mechanism of CG.The evaluations of computed tomography(CT) and clinical manifestation were limited to distinguish CG from cholesteatoma or other neoplasm,while the MRI can be of great value to characteristic diagnosis.
Keywords:Cholesterol granuloma  Suppurative otitis media  Hearingdisorders
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