| 三七总皂苷缓释片的初步工艺研究 |
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| 引用本文： | 洪燕龙,吴清,杜守颖. 三七总皂苷缓释片的初步工艺研究[J]. 北京中医药大学学报, 2004, 27(3): 75-77 |
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| 作者姓名： | 洪燕龙 吴清 杜守颖 |
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| 作者单位： | 北京中医药大学中药学院,北京,100102;北京中医药大学中药学院,北京,100102;北京中医药大学中药学院,北京,100102 |
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| 基金项目： | 北京中医药大学校科研和教改项目 |
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| 摘 要： | 目的采用新型缓释材料及固体分散技术制备三七总皂苷缓释片.方法以人参皂苷Rg1和Rb1为指标,采用单因素法考察辅料对缓释作用的影响,并优化处方.结果选择乙基纤维素(EC)为缓释部分的辅料,并以聚乙二醇4000(PEG-4000)为速释部分的辅料.结论初步实现了三七总皂苷缓释片的缓释效果.
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| 关 键 词： | 三七总皂苷 缓释片 人参皂苷 高效液相 |
| 修稿时间： | 2003-11-09 |
Initial Research on the Technology for Preparing Slow-Release TotalNotoginsenoside Tablets |
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| Hong Yanlong,Wu Qing,Du Shouying. Initial Research on the Technology for Preparing Slow-Release TotalNotoginsenoside Tablets[J]. Journal of Beijing University of Traditional Chinese Medicine, 2004, 27(3): 75-77 |
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| Authors: | Hong Yanlong Wu Qing Du Shouying |
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| Abstract: | Objective To find new slow-release adjuvant materials for preparing Slow-Release Total Notoginsenoside Tablets (SRTNT) by the solid-dispersing technology. Method Ginsenosides Rg 1 and Rb 1 were taken as criteria, the one-factor method was used to examine the influence of adjuvant materials on slow-release action, and the recipe of SRTNT was optimized at the same time.Result EC was chosen as a slow-release adjuvant material and PEG4000 as a rapid-release adjuvant material.Conclusion The slow-release effect of SRTNT is basically achieved. |
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| Keywords: | Total Notoginsenoside Slow-Release Tablet Ginsenosides Rg 1 and Rb 1 HPLC |
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