(2-Ethoxyethoxy)acetic acid: An unusual compound found in the gas chromatographic analysis of urinary organic acids |
| |
| Authors: | J.P. Kamerling M. Duran L. Bruinvis D. Ketting S.K. Wadman C.J. de Groot F.A. Hommes |
| |
| Affiliation: | 1. University Children''s Hospital “Het Wilhelmina Kinderziekenhuis”, Nieuwe Gracht 137, Utrecht, The Netherlands;2. Department of Pediatrics and Laboratory for Developmental Biochemistry, State University of Groningen, Groningen, The Netherlands |
| |
| Abstract: | An unknown acidic compound was detected in a number of urine samples from patients with a suspected metabolic disorder and some patients treated with chemotherapy. The structure of this compound has been characterized as (2-ethoxyethoxy)acetic acid, using a gas chromatography/mass spectrometry/ computer system.The authentic compound was synthesized and compared with the unknown. Urinary (2-ethoxyethoxy)acetic acid is assumed to be formed endogenously from an exogenous precursor, probably 2-(2-ethoxyethoxy)ethanol. |
| |
| Keywords: | To whom correspondence should be addressed. |
| 本文献已被 ScienceDirect 等数据库收录！ |
