New aromatic compounds from the marine mangrove Bruguiera gymnorrhiza |
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| Authors: | Han Li Huang Xueshi Sattler Isabel Moellmann Ute Fu Hongzheng Lin Wenhan Grabley Susanne |
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| Affiliation: | Hans-Kn?ll Institute for Natural Products Research, Jena, Germany. |
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| Abstract: | The phytochemical investigation of the stem of Bruguiera gymnorrhiza yielded five new aromatic compounds (1-5), of which the bruguierols A - C (1-3) represent a new structural skeleton in natural product chemistry. All structures have been determined by NMR spectroscopic studies. Among them, 3 showed moderate activity against Gram-positive and Gram-negative bacteria including mycobacteria and resistant strains (MICs 12.5 microg/mL). |
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