独活寄生汤配合针刺治疗膝骨性关节炎30例临床观察

目的：观察独活寄生汤配合针刺治疗膝骨性关节炎的临床疗效。方法：将60例患者随机分成2组,治疗组30例采用独活寄生汤配合针刺治疗,对照组30例单纯采用针刺及西药治疗。2组均以10d为1个疗程,2个疗程评价疗效。观察2组治疗后临床证候疗效、Lysholm膝关节功能评分（Lysholm Knee Score,LKSS）及不良反应变化。结果：治疗组与对照组总有效率分别为86.7%和63.3%（P〈0.05）;2组LKSS比较,治疗结束LKSS均高于治疗前,差异有统计学意义（P〈0.05）;治疗10d（次）后治疗组LKSS低于对照组（P〉0.05）;治疗结束时治疗组LKSS高于对照组;差异有统计学意义（P〈0.05）。不良反应治疗组明显低于对照组。结论：独活寄生汤配合针刺治疗膝骨性关节炎能改善血液循环,减轻肌肉痉挛、缓解疼痛,恢复膝骨性关节功能。

Clinical Observation on Duhuojisheng Decoction Combined with Acupuncture Treating 30 Cases of Knee Osteoarthritis

Objective： To observe the clinical curative effect of Duhuojisheng decoction combined with acupuncture in the treatment of osteoarthritis of the knee. Methods： Sixty patients were randomly divided into 2 groups. The 30 cases in treatment group were treated with Duhuojisheng decoction combined with acupuncture treatment. The 30 cases in the control group received acupuncture and western medicine. One treatment course lasted 10 days and clinical evaluation was made after 2 courses. Therapeutic effect,Lysholm Knee Score,LKSS and adverse reactions after the treatment were observed. Results： The total effective rates of the treatment group and the control group were respectively 86. 7% and 63. 3%（ P〈0. 05）. Comparing the changes of LKSS,at the end of treatment,the LKSS of both groups were higher than that before the treatment. The difference was statistically significant（ P〈0. 05）. After 10 days（ times） of treatment,the LKSS of the treatment group was lower than that of the control group（ P〈0. 05）. At the end of the whole treatment,the LKSS of the treatment group was higher than that the control group. The difference was statistically significant（ P〈0. 05）. Adverse reactions of the treatment group was significantly lower than that of the control group. Conclusion： Duhuojisheng decoction combined with acupuncture in the treatment of knee osteoarthritis would improve blood circulation,relieve muscle spasm,pain and promote recover of knee joint function.