| 聚戊烯醇同系物体外对肿瘤细胞的抑制作用研究 |
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| 作者姓名： | 李海涛 许立 盛玉清 王成章 郑光耀 |
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| 作者单位： | 南京中医药大学药学院 江苏南京210046(李海涛, 许立, 盛玉清), 中国林业科学研究院林产化学工业研究所 江苏南京210037(王成章, 郑光耀) |
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| 摘 要： | 目的研究聚戊烯醇同系物对肿瘤细胞的抑制作用。方法采用MTT法,观察聚物烯醇同系物对SGC-7901人胃癌细胞株、LoVo人结肠腺癌细胞株、Hela人宫颈癌细胞株的抑制作用。结果P-1、P-2体外对LoVo、SGC-7901和Hela细胞株细胞株的抑制率较低,P-3体外对LoVo、SGC-7901和Hela细胞株抑制率较高,并随浓度和时间的增加抑制作用也呈增强趋势。结论聚戊烯醇同系物对肿瘤细胞均呈不同程度的抑制作用。
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| 关 键 词： | 银杏叶 聚戊烯醇 人胃癌细胞株 人结肠腺癌细胞株 人宫颈癌细胞株 |
| 文章编号： | 1000-5005（2007）06-0368-03 |
| 收稿时间： | 2007-06-11 |
| 修稿时间： | 2007-07-08 |
Inhibiting Effect of Pentenoi Homologens on In Vitro Tumor Cells |
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| Authors: | LI Hai-tao Xu Li SHENG Yu-qing WANG Cheng-zhang ZHENG Guang-yao |
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| Institution: | 1 Pharmacology College of Nanjing University of Traditional Chinese Medicine, Nanjing , Jiangsu, 210046, China ;2 Research Institute of Forestry Chemical Industry, China Forestry Research Institute, Nanjing, Jiangsu, 210037, China |
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| Abstract: | OBJECTIVE To investigate the inhibiting effect of pentenol homologens on tumor cells.METHOD MTT method was adopted to observe the inhibiting effect of pentenol homologens on SGC-7901 human cancer cell strains,LoVo human colon adenocarcinoma cell strains and Hela human uterine cervix cancer cell strains.RESULT P-1 and P-2 had relatively low inhibiting effect on the cancer cell strains, while P-3 had relatively high inhibiting effect,which tended to increase with the increase of concentration and time.CONCLUSION Pentenol homologens has different degrees of inhibiting effect on tumor cells. |
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| Keywords: | Folium Ginkgo pentenol human cancer cell strains human colon adenocarcinoma cell strains human uterine cervix cancer cell strains |
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