No influence of number of donor CFU-GM on granulocyte recovery in bone marrow transplantation for acute leukemia |
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| Authors: | A Torres M C Alonso J L Gomez-Villagran M R Manzanares F Martinez P Gomez J M Garcia P Andres C Gomez M A Torre F Velasco the Córdoba Bone Marrow Transplantation Team |
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| Institution: | (1) Department of Hematology,  Reina Sofía Hospital, Córdoba, Spain;(2) Faculty of Medicine, University of Córdoba, Córdoba, Spain |
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| Abstract: | Summary The possible interrelation between infused bone marrow CFU-GM and peripheral granulocyte recovery was studied in 16 patients transplanted for acute leukemia. The influence of several clinical events that could modify the graft fate were also analysed. Our results show that: 1) There was no correlation between the number of infused nucleated cells and granulocyte recovery. 2) There was no correlation between the number of infused CFU-GM and granulocyte regeneration. 3) There were significant differences between the day of engraftment in patients with clinically documented HSV infection compared to patients without infection.Abbreviations BMT
Bone marrow transplantation
- CFU-GM
Colony forming units granulocytic-macrophagic
- GvHD
Graft versus host disease
- HVS
Herpes virus simplex
- PMN
Polymorphonuclears
- UPN
Unipersonal number |
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| Keywords: | Bone marrow transplantation Acute leukemia CFU-GM Granulocyte compartment |
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