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E170检测血清TPSA、FPSA及FPSA/TPSA在前列腺疾病诊断中的应用价值
引用本文:秦辛玲,黄立伟,罗云,王玉春.E170检测血清TPSA、FPSA及FPSA/TPSA在前列腺疾病诊断中的应用价值[J].华夏医学,2009,22(1).
作者姓名:秦辛玲  黄立伟  罗云  王玉春
作者单位:1. 桂林医学院附属医院检验科,广西,桂林,541001
2. 广西壮族自治区南溪山医院检验科,广西,桂林,541002
摘    要:目的:探讨E170检测血清TPSA、FPSA及FPSA/TPSA比值在前列腺疾病诊断中的应用价值.方法:应用E170电化学发光免疫分析(ECLIA)法检测正常对照组(40例)、前列腺炎组(78例)、前列腺增生组(64例)及前列腺癌组(35例)血清TPSA、FPSA含量及FPSA/TPSA.结果:前列腺癌组TPSA、FPSA、FPSA/TPSA与其他3组比较差异均有显著性(P<0.05),前列腺增生组TPSA、FPSA、FPSA/TPSA与另两组(正常组和前列腺炎组)比较差异也有显著性(P<0.05),而正常组与前列腺炎组之间比较差异无显著性(P>0.05);在TPSA不同水平阶段,前列腺增生与前列腺癌所占比率不同(P<0.05);在不同年龄阶段,前列腺癌的所占比率不同(P<0.05).结论:应用ECLIA检测TPSA、FPSA含量及FPSA/TPSA是提高前列腺疾病诊断与鉴别诊断更为有效的方法,尤其对前列腺癌诊断更有意义.

关 键 词:前列腺疾病  FPSA、FPSA/TPSA

Application of serum TPSA,FPSA detections and FPSA/TPSA evaluation for diagnosis and therapy of prostatic diseases with E170 technique
QIN Xin-ling,HUANG Li-wei,LUO Yun,et al..Application of serum TPSA,FPSA detections and FPSA/TPSA evaluation for diagnosis and therapy of prostatic diseases with E170 technique[J].Acta Medicinae Sinica,2009,22(1).
Authors:QIN Xin-ling  HUANG Li-wei  LUO Yun  
Institution:QIN Xin-ling,HUANG Li-wei,LUO Yun,et al.Department of Laboratory,The Affiliated Hospital of Guilin Medical College,Guilin 541001,China
Abstract:Objective:To investigate the application of TPSA,FPSA concent rations and FPSA/TPSA value for diagnosis and therapy of prostatic diseases detected with E170 electrochemiluminescent immunoassay(ECLIA) technique.Methods:40 cases of normal individuals were used as control group,78 patients with prostatitisas prostatitis group,64 patients with prostatic hyperplasia as BPH group and 35 patients with prostate cancer asprostate cancer group.TPSA,FPSA concent rations and FPSA/TPSA value were detected with ECLIA tec...
Keywords:E170  TPSA
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