弥漫性轴索损伤74例临床分析

目的探讨弥漫性轴索损伤（diffuse axonal injury，DAI）的发病机制、临床特点、诊断、治疗及预后。方法回顾性分析74例DAI病人的临床资料。结果按GOS评分：治愈23例（31．1％），中残27例（36．5％），重残或植物生存16例（21．6％），死亡8例（10．8％）。结论弥漫性轴索损伤的诊断要结合临床表现和动态影像学检查，GCS评分、昏迷时间、瞳孔变化、出血灶部位是判断预后的重要指标，早期正确诊断和有效综合治疗是改善病人预后的关键。

Analysis of Clinical Characteristics of 74 Patients with Diffuse Axonal Injury

Objective To investigate the clinical characteristics,diagnosis,treatment and prognosis of cerebral diffuse axonal injury （DAI）.Method The clinical materials of 74 cases of DAI were analyzed retrospectively. Result Based on Glasgow Coma Scale, the outcome were good 23（31.1%）,medium deformity 27 （36.5%）,severe deformity or vegetal condition 16（21.6%）,death 8（10.8%）.Conclusion The GCS score,persisting coma and pupil change can be an important index to measure the prognosis of DAI.Early diagnoses and comprehensive treatment can improve prognosis significantly.