米非司酮与毓婷用于紧急避孕的疗效比较研究

目的比较米非司酮与毓婷用于紧急避孕的疗效。方法随机选择无防护性生活或避孕失败后72h内的要求紧急避孕育龄妇女200例,随机选择100例给予口服米非司酮作为观察组;另外100例给予口服毓婷作为对照组,观察两组的避孕效果及不良反应。结果观察组的妊娠率为0%,对照组为6%,前者避孕效果优于对照组,差异有统计学意义(P<0.05),且不良反应略低,但差异无统计学意义(P>0.05)。结论米非司酮较毓婷用于紧急避孕,更具有安全、有效及不良反应少的特点,值得临床推广。

The comparison of the efficacy of mifepristone for emergency contraception with levonorgestrel tablets

Objective To compare the efficacy of mifepristone for emergency contraception with levonorgestrel tablets.Methods Among 200 women who required emergency contraception due to unprotected sexual behavior or failure in contraception within 72 hours,100 women orally took mifepristone as observing group,while another 100 women orally took levonorgestrel tablets as compared group.The efficacy and side-effects were observed.Results The pregnancy rate of observing group was 0%,compared group was 6%.The efficacy of the former was better than compared group with marked difference(P<0.05),There were milder side-effects,but no marked difference(P>0.05).Conclusion Mifepristone is a safe,efficient treatment with mild side-effects and it is worth popularizing for emergency contraception.