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甘丙肽在癫痫及癫痫持续状态患儿血浆中水平变化及意义
引用本文:及立立,王文兰. 甘丙肽在癫痫及癫痫持续状态患儿血浆中水平变化及意义[J]. 内蒙古医学杂志, 2010, 42(4): 400-402
作者姓名:及立立  王文兰
作者单位:1. 内蒙古医学院,内蒙古,呼和浩特,010059
2. 内蒙古自治区医院儿科,内蒙古,呼和浩特,010017
摘    要:目的:探讨甘丙肽在癫痫患儿惊厥过程中的含量变化及临床意义。方法:通过酶联免疫法(ELISA)测定33例癫痫组、15例癫痫持续状态组和30例正常对照组患儿血浆甘丙肽的含量,并进行比较分析。结果:癫痫组患儿血浆甘丙肽含量明显高于癫痫持续状态组和正常对照组(F=205.911,P〈0.05);癫痫持续状态组与正常对照组之间差异无统计学意义(t=0.475,P〉0.05)。结论:甘丙肽在癫痫患儿惊厥过程中含量增高,表明甘丙肽与癫痫关系密切,可能起到抗惊厥的作用。

关 键 词:甘丙肽  癫痫  血浆

Plasmatic Galanin Changes in Children with Epilepsy and Status Epilepticus
JI Li-li,WANG Wen-lan. Plasmatic Galanin Changes in Children with Epilepsy and Status Epilepticus[J]. Inner Mongolia Medical Journal, 2010, 42(4): 400-402
Authors:JI Li-li  WANG Wen-lan
Affiliation:1.Department of Postgraduate 2007,Inner Mongolia Medical College,Huhhot 010059 China;2.Department of Pediatric,Inner Mongolia Hospital,Huhhot 010017 China)
Abstract:Objective:To discuss the galanin content changes and clinical significance,of children with seizure in the epileptic.Method:To determine the galanin contents in plasma by enzyme-linked immunosorbent assay(ELISA),It divide three groups,33 cases of epilepsy group、15 cases with status epilepticus group and 30 cases of normal control group.Results: Plasma of Children with epilepsy group were significantly higher than that galanin status epilepticus group and the normal control group(F=205.911,P0.05);Status epilepticus group and normal control group,no significant difference(t=0.475,P0.05).Conclusion: The relationship is closely between galanin and epilepsy,so galanin may play an anticonvulsant role.
Keywords:Galanin  Epilepsy  Plasma
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