Heterogeneity of rat cardiac cells of defined origin in single cell culture |
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| Authors: | Carol R. Norwood Aldo R. Castaneda William I. Norwood |
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| Affiliation: | 1. Department of Cardiovascular Surgery, Children''s Hospital Medical Center, Boston, MA 02115, U.S.A.;2. Department of Surgery, Harvard Medical School, Boston, MA 02115, U.S.A. |
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| Abstract: | Cells derived from tissue containing different elements of the conduction system of the neonatal rat heart have been isolated and maintained separately in culture. The autorhythmic cells are of three morphological types, one of which has not previously been described, and the distribution of these types is dependent on the anatomic origin of the cells. The heterogeneity in morphology and intrinsic rate of contraction is consistent with in vivo observations. |
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| Keywords: | Cultured cardiac cells Culturing of anatomic sub-populations of cardiac cells Cardiac cell morphology Cardiac conduction system Purkinje cells |
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