| 环孢霉素A对缺血再灌注心肌的保护作用与CD4+T细胞的关系 |
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| 引用本文： | 文兵,杨双强.环孢霉素A对缺血再灌注心肌的保护作用与CD4+T细胞的关系[J].广东医学,2011,32(6):691-694. |
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| 作者姓名： | 文兵 杨双强 |
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| 作者单位： | 重庆医科大学附属第一医院胸心外科 |
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| 摘 要： | 目的 观察环孢霉素A对缺血再灌注心肌的影响,并探讨其与CD4+T细胞之间的关系.方法 将32只SD大鼠随机分为4组(n=8): 假手术组(Sham)、缺血再灌注(I/R)模型组、环孢霉素(CsA)组、CsA+5-羟基葵酸盐(5-HD)组.CsA、CsA+5-HD组给予CsA 15 mg/kg及1 mL生理盐水腹腔注射,...
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| 关 键 词： | 环孢霉素 CD4+T细胞 钙调神经磷酸酶 心肌缺血再灌注损伤 大鼠 |
Correlation study between the protective effect of cyclosporine A on myocardial ischemia-reperfusion injury and CD4~+ T cell |
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| WEN Bing,YANG Shuang-qiang.Correlation study between the protective effect of cyclosporine A on myocardial ischemia-reperfusion injury and CD4~+ T cell[J].Guangdong Medical Journal,2011,32(6):691-694. |
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| Authors: | WEN Bing YANG Shuang-qiang |
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| Institution: | WEN Bing,YANG Shuang-qiang.Department of Cardiothoracic,The First Affilated Hospital of Chongqing Medical University,Chongqing 400016,China |
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| Abstract: | Objective To study the protective effect of cyclosporine A on myocardial ischemia-reperfusion injury(MIRI) in rats,and to investigate the correlation between the protective effects and CD4+ T cells.WEN Bing,YANG Shuang-qiang.Department of Cardiothoracic,The First Affilated Hospital of Chongqing Medical University,Chongqing 400016,ChinaMethods Thirty-two rats were randomly divided into four groups(n=8): sham operation group,ischemic-reperfusion(I/R) group,CsA group and CsA+5-HD group.Intraperitoneal injectio... |
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| Keywords: | CsA CD4 T cells CaN myocardial ischemia reperfusion injury rat |
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