| 一阶导数光谱法测定奥硝唑凝胶中主药的含量 |
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| 引用本文： | 吕红,彭彦,林怡,晋园. 一阶导数光谱法测定奥硝唑凝胶中主药的含量[J]. 中国药房, 2007, 18(10): 776-777 |
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| 作者姓名： | 吕红 彭彦 林怡 晋园 |
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| 作者单位： | 1. 华中科技大学同济医学院药学院,武汉市,430030;东风汽车公司襄樊医院药剂科,襄樊市,441004
2. 华中科技大学同济医学院药学院,武汉市,430030 |
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| 摘 要： | 目的:建立测定奥硝唑凝胶中主药含量的方法。方法:采用一阶导数光谱法,在259nm和299nm波长处测定凝胶中奥硝唑的含量。结果:奥硝唑线性范围为4.01～44.1μg.mL-1,平均回收率为101.6%(RSD=1.3%)。结论:本方法精密度、准确度均能满足奥硝唑凝胶质量控制要求。
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| 关 键 词： | 奥硝唑凝胶 一阶导数光谱法 含量测定 |
| 文章编号： | 1001-0408(2007)10-0776-02 |
| 收稿时间： | 2006-12-29 |
| 修稿时间： | 2007-02-12 |
Determination of Ornidazole Gel by First Order Derivative Spectrophotometry |
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| LU Hong,PENG Yan,LIN Yi,JIN Yuan. Determination of Ornidazole Gel by First Order Derivative Spectrophotometry[J]. China Pharmacy, 2007, 18(10): 776-777 |
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| Authors: | LU Hong PENG Yan LIN Yi JIN Yuan |
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| Abstract: | OBJECTIVE:To establish a method for determining the content of Ornidazole gel by first-order derivative spectrophotometry.METHODS:The first-order derivative spectrophotometry was used to determine the content of Ornidazole gel at a wavelength of 259nm and 299nm.RESULTS:The linear range of Ornidazole was 4.01～44.1μg·mL-1.The average recovery was 101.6%,with RSD of 1.3%.CONCLUSIONS:This method can meet the requirements for quality control of Ornidazole gel both in terms of precision and accuracy. |
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| Keywords: | Ornidazole gel First order derivative spectrophotometry Content determination |
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