203例新生儿高胆红素血症对心肌酶CK、CK—MB活性影响的临床研究

目的：探讨新生儿高胆红素血症对心肌酶活性的影响，以及与心肌损害的关系。方法：203例新生儿高胆红素血症作为治疗组，130例同期出生的正常新生儿作为对照组。监测两组治疗前后的心肌酶CK、CK—MB值。结果：胆红素含量越高，心肌酶活性也高。治疗组治疗前后心肌酶谱值比较，差异有统计学意义（P〈0．05）。结论：临床儿科医生在治疗新生儿黄疸患儿时，应将心肌酶谱列为常规检查项目，避免新生儿黄疸患儿因心肌损害而死亡。

The clinical research on the enzymes CK, CK-MB activity of 203 cases with neonatal hyperbilirubinemia

Objective: To discuss the enzymes CK, CK-MB activity of 203 cases with neonatal hyperbilirubinemia,as well as the relationship between myocardial damage. Methods: 203 cases with neonatal hyperbilimbinemia as a treatment group, 130 cases of the same period replacement of the normal newborn as a control group. To monitor the two groups before and after enzyme CK, CK-MB values, and to compare and analyze.Results: The higher the concentration of biliru-bin, enzyme activity was also high, and with the decline in total bilirubin level, the myocardial creatine phosphate and cre-atine kinase-MB was also gradually declining. Before and after treatment enzymogram value of the treatment group were compared, and there were significant difference (P<0.05).Condusion:Paediatricians in the treatment of clinical neonatal jaundice in children should be as routine examination enzymagram projects, to avoid children with neonatal jaundice and death due to myocardial damage.