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Percutaneous angioplasty for atherosclerotic renal artery disease: Effect on renal function in azotemic patients
Authors:Peter M. T. Pattynama  Gary J. Becker  Judy Brown  Gerald Zemel  James F. Benenati  Barry T. Katzen
Affiliation:(1) Department of Radiology, Leiden University Hospital, Building 1-C3Q, Rijnsburgerweg 10, 2333 AA Leiden, The Netherlands;(2) Miami Vascular Institute, Baptist Hospital of Miami, 8900 N. Kendall Drive, 33176 Miami, FL, USA
Abstract:Purpose We studied the effect of percutaneous transluminal renal angioplasty (PTRA) on renal function in azotemic patients with atherosclerotic renal artery stenosis.Methods The results of PTRA were analyzed retrospectively in 40 patients. There were 61 stenoses, 54 of which received balloon angioplasty; 7 had stent placement during the initial procedure, 6 for recurrent stenosis 6–18 months after PTRA.Results Technical success was achieved in 95% of cases. The complication rate was 15%, compared to 6% in nonazotemic patients. Mean creatinine rose from 1.9 ± 0.15 mg/dl (mean ± SEM) to 2.4 ± 0.17 mg/dl during the year before PTRA, stabilizing at 2.5 ± 0.57 mg/ dl for 1 year after PTRA. PTRA was clinically successful in 60% of patients; 40% showed further deterioration of renal function. Clinical failure was associated with residual renal artery stenosis and presence of intermittent claudication.Conclusion We conclude that PTRA helps salvage renal function in patients with azotemia and atherosclerotic renal artery stenosis.
Keywords:Arteries transluminal angioplasty  Renal arteries  stenosis or obstruction Kidney function  Kidney failure
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