综合性康复干预治疗慢性肾功能衰竭的疗效评价

目的观察50例慢性。肾功能衰竭(CRF)患者经综合康复治疗后的临床疗效，并探讨综合治疗对CRF相关指标的影响。方法将50例CRF患者按1：1配对设计分为康复组及对照组。对照组患者采用单纯药物治疗，康复组患者除常规药物治疗外，还联用一系列康复治疗措施，如与患者建立良好沟通渠道，指导其学习健康知识，进行适量有氧运动等。采用症状自评量表(SCL-90)及CRF专用生活质量量表进行疗效评定，并在治疗前、后分别检测患者收缩压(SBP)、舒张压(DBP)、血清肌酐(SCr)、尿素氮(BUN)及肌酐清除率(Ccr)等指标。结果与对照组比较，康复组患者经综合康复治疗1年后，其心理功能及生活质量相关指标均明显改善，SBP、DBP明显下降，差异有显著性意义；SCr、BUN、Ccr无明显变化，2组间差异无显著性意义。结论对慢性肾功能衰竭患者实施综合康复治疗，有利于改善患者心理功能，降低血压，提高其生活质量，即综合治疗的疗效明显优于单纯药物治疗。

The effectiveness of comprehensive rehabilitation treatment in patients with chronic renal failure

Objective To observe the therapeutic effects of comprehensive rehabilitation treatment in patients with chronic renal failure (CRF). Methods Fifty patients with CRF were randomly and equally divided into a rehabilitation group and a control group. Those in the rehabilitation group were intervened with comprehensive rehabilitation protocol including regular counseling, health education and adequate aerobic exercise in addition to routine medications, while those in the control group with the routine medications only. The therapeutic effects were evaluated by means of Symptom Check List- 90(SCL- 90) and the questionnaire about quality of life (QOL) for patients with CRF, as well as such biochemical parameters as SCr, BUN, Ccr, DBP and SBP before and after treatment. Results Compared with those in the control group, the physiological capability and other relevant parameters of QOL in the rehabilitation group were significantly improved after one year of comprehensive rehabilitation, while SBP and DBP significantly decreased. There was no statistically significant changes of the concentrations of Scr, Bun, and Ccr. Conclusion Comprehensive rehabilitation intervention is superior to routine drug therapy in terms of improving the physiological capability, decreasing the BP and improving the QOL of the CRF patients.