生物标志物在动脉粥样硬化相关性脑卒中的研究进展

动脉粥样硬化相关性脑卒中的高发病率、高致残率及高病死率给社会和患者及患者家属带来严重影响,因此,及时有效的诊断对临床医师准确评估病情的危险因素,并选择有效的治疗方法尤为重要。研究表明,越来越多的蛋白、微小RNA及脂质因子的表达变化与动脉粥样硬化相关性脑卒中的发生、发展和预后密切相关,可能是脑卒中潜在生物标志物。本文通过查阅国内外文献,对动脉粥样硬化相关性脑卒中的生物标志物进行了系统的最新综述,为防治动脉粥样硬化相关性脑卒中提供新思路。

Research progress of biomarkers in atherosclerotic related stroke

The high incidence, high disability rate and high mortality of atherosclerotic related stroke have a serious effect on the society, patients and their families. Therefore, timely and effective diagnosis is particularly important for clinicians to accurately evaluate the risk factors of the disease and select effective treatment methods. Research shows that the expression changes of more and more protein, microRNA and lipid factors are closely related to the occurrence, development and prognosis of atherosclerotic related stroke, which may be potential biomarkers of stroke. In this paper, the biomarkers of atherosclerotic related stroke were reviewed systematically by consulting the domestic and foreign literature, in order to provide new ideas for the prevention and treatment of atherosclerotic related stroke.