降钙素原在尿路感染定位中的临床意义

目的探讨降钙素原（PCT）在尿路感染定位中的临床意义。方法用免疫定量法测定114例尿路感染患者及40例健康者的降钙素原（PCT）、C反应蛋白（CRP）。结果上尿路感染组患者血清降钙素原（PCT）水平明显高于下尿路感染患者组（P〈0.01）,PCT对上尿路感染诊断的敏感性为81.1%,特异性为85.5%,阳性预测值为80.3%,阴性预测值为92.5%,均高于CRP。结论 PCT对尿路感染的定位有临床意义。

Clinical Significance of Procalcitonin (PCT) in Locating the Infection Position in Urinary Tract Infection

Objective To explore the clinical significance of procalcitonin(PCT) in the infection location of urinary tract infection(UTI).Methods The concenstrations of PCT and C-reactive protein(CRP) in serum from 114 patients with UTI were detected by immunolumino-metric assay.Results The serum PCT level in patients with upper urinary tract infection was significantly higher than that in those with lower urinary tract infection(P<0.01).The sensitivity,specificity,positive predictive value and negative predictive value of PCT for diagnosis of upper urinary tract infection were 81.1%,85.5%,80.3% and 92.5% respectively,which were all higher than those of CRP.Conclusions Serum PCT can be used as a marker to differentiate the upper and lower urinary tract infection.