内皮祖细胞在动脉粥样硬化易损斑块中的作用

目的 动脉粥样硬化易损斑块是急性冠状动脉综合征和心脏缺血性猝死的重要病理基础.研究证实易损斑块表面大面积内皮细胞受损和血栓形成,内皮受损后可引起炎症因子瀑布样反应、单核细胞浸润和血管平滑肌细胞增生,进而促发动脉粥样硬化易损班块形成,故修复受损血管内皮、促使血管重新内皮化已经成为防止动脉粥样硬化的重要课题.近年研究认为,...

Review of Role of Endothelial Progenitor Cells in the Process of Atherosclerotic Vulnerable Plaque

Atherosclerotic vulnerable plaque is considered as an important pathologic basis of acute coronary syndrome and sudden cardiac ischemic death.Vulnerable plaque is characterized with endothelial denudation and thrombosis.The mechanisms of vulnerable plaque are poorly understood.Recent researches demonstrated that endothelial progenitor cells play an important role in repair of injured endothelium.So the role of endothelial progenitor cells in the process of atherosclerotic vulnerable plaque is worth investig...