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罗库溴铵预注效果的临床研究
引用本文:陈锡明,杭燕南,孙大金. 罗库溴铵预注效果的临床研究[J]. 临床麻醉学杂志, 1999, 15(3): 134-136
作者姓名:陈锡明  杭燕南  孙大金
作者单位:上海第二医科大学附属仁济医院麻醉科,200001
摘    要:目的:研究较库溴争的预注效果。方法:ASAⅠ-Ⅱ级择期全麻手术46例,男25例,女21例,分为三组。Ⅰ组用罗库溴铵预注法导插管,应用正交试验L(3^7)方法,观察0.045、0.06、0.075mg/kg三种不同水平的预注量(PD),2、3、4分钟预注时间(PI)及0、3、0.45、0.6mg/kg插管剂量(ID)地预注效果的影响,Ⅱ组(n=18)用罗库溴铵0.3、0.45、0.6mg/kg常规诱

关 键 词:罗库溴铵  神经肌肉阻滞  全麻

Assessment of the Effects of Priming Rocuronium
Chen Ximing,Hang Yannan,Sun Dajin. Assessment of the Effects of Priming Rocuronium[J]. The Journal of Clinical Anesthesiology, 1999, 15(3): 134-136
Authors:Chen Ximing  Hang Yannan  Sun Dajin
Abstract:Objectives: The study was designed to assess the effects of priming rocuronium on the onset time under general anesthesia. Methods: The effects of three priming doses of rocuronium (PD:0045,006or0075mg/kg), priming intervals (PI:2,3 or4 min) and intubation doses (ID:03,045 or 06mg/kg) were observed using orthogonal design in 18 patients. Other 18 patients received conventional induction with 045,06 or 075mg/kg of rocuronium and 10 patients received 1mg/kg of suxamethonium as control. Results: The effects of priming rocuronium was evident (P<005), ID and PD were important factors. Conclusion: PD006mg/kg, PI 2min and ID06mg/kg might be reasonable mode of priming rocuronium.
Keywords:RocuroniumNeuromuscular blockGeneral anesthesia
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