Abstract: | The aim of this outlook was to study the application of Misoprostol in obstetrics and gynaecology. Because this preparation is not approved for use in Bulgaria, publications on the topic from various journals cited in Medline, Cochrane library, Nature, Science, Lancet, GyneWeb and others have been taken into consideration. Indications, methods of administration, dosages and side effects in use of this drug were described. |