Genetic risk factors of chronic obstructive pulmonary disease |
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Authors: | Joos Ladina Paré Peter D Sandford Andrew J |
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Affiliation: | Departement Innere Medizin, Kantonsspital Basel, Switzerland. ljoos@uhbs.ch |
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Abstract: | Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). However, only a minority of cigarette smokers develop symptomatic disease. Family and twin studies suggest that genetic factors also contribute to the development of COPD. We present a detailed literature review of the genes which have been investigated as potential risk factors for this disease. |
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