肝硬化并自发性细菌性腹膜炎的临床分析

目的探讨肝硬化合并自发性细菌性腹膜炎患者的病原菌情况及其临床特点。方法选取该院134例肝硬化并发自发性细菌性腹膜炎患者的临床资料、细菌培养和药敏结果进行回顾性分析。结果在134例肝硬化并发自发性细菌性腹膜炎患者中,67例患者并发肝肾综合征、肝性脑病、电解质紊乱、消化道出血及其他部位感染等并发症;腹水细菌培养阳性19例（14.2%）病原菌为革兰阴性菌13例,占68.4%。临床治愈：52例（38.8%）,有效54例（40.3%）,无效28例（20.9%）。结论早期诊断、及时应用抗生素及积极采取综合性治疗是改善肝硬化合并自发性细菌性腹膜炎预后的关键。

Clinical Analysis of the Patients of Liver Cirrhosis Combined with Sponta-neous Bacteria1 Peritonitis

Objective To study the pathogens and clinical features of the patients of liver cirrhosis combined with spontaneous bacterial peritonitis （SBP）. Methods The clinical data, bacterial culture and drug sensitivity results of 134 patients with cirrhosis complicated by SBP admitted in our hospital were selected and retrospectively analyzed. Results Of the 134 patients with liver cirrhosis complicated by spontaneous bacterial peritonitis, 67 patients were concurrent by hepatorenal syndrome, hepatic encephalopathy, electrolyte disturbances, gastrointestinal bleeding, infections in other sites and other complications. The ascites bacterial culture was positive in 19 cases （14.2%）, and the pathogens of 13 cases were Gram-negative bacteria, accounting for 68.4%. 52 cases （38.8%） were cured clinically, the treatment was effective in 54 cases （40.3%）, ineffective in 28 cases （20.9%）. Conclusion Early diagnosis, timely application of antibiotics and active adoption of comprehensive treatment are the key to improving the prognosis of the patients with liver cirrhosis complicated by spontaneous bacterial peritonitis.