明胶海绵粉末栓塞犬髂内动脉

背景：明胶海绵已成为骶骨肿瘤术前栓塞的首选材料,但针对小颗粒明胶海绵对栓塞效果及栓塞后并发症的影响未见明确报道。 目的：观察小颗粒明胶海绵栓塞犬双侧髂内动脉后手术出血量变化和并发症情况。 方法：用直径为50-150 μm明胶海绵粉末对15只犬行双侧髂内及骶正中动脉栓塞,分别于栓塞后1,2,3 d模拟骶骨肿瘤手术测量出血量变化;病理观察栓塞区膀胱、直肠、臀部肌及坐骨神经变化。 结果与结论：栓塞后第3天出血量高于第1,2天(P < 0.05),栓塞后第1天与第2天出血量差异无显著性意义(P > 0.05)。在运用直径为50-150 μm明胶海绵粉末栓塞犬双侧髂内及骶正中动脉时,最小动脉是50 μm的微动脉,但主要集中在100-200 μm小动脉,数字减影血管造影下显示栓塞双侧髂内及骶正中动脉近端血管级别为其一级分支,此时犬盆腔脏器组织无明显变化。

Embolization of dog’s bilateral internal iliac arteries with gelfoam powder

BACKGROUND:Gelfoam has become the preferred embolization agent for preoperative embolism in the operation of sacral tumor, but the contribution of small gelfoam to embolization effectiveness and postoperative complications has not been definitely reported. OBJECTIVE:To observe the changes in intraoperative bleeding and complications following embolization of dog’s bilateral internal iliac arteries with gelfoam powder. METHODS:The bilateral internal iliac and median sacral arteries of fifteen dogs were embolized using gelfoam powder with a diameter of 50-150 μm. Then, the operation of sacral tumor was imitated to measure intraoperative bleeding at 1, 2, and 3 days after embolization, observing pathological alteration of pelvic organs. RESULTS AND CONCLUSION:The mean intraoperative bleeding was higher at 3 days than at 1 and 2 days (P < 0.0.5), but it was no difference at 1 and 2 days (P > 0.05). When gelfoam power with a diameter of 50-150 μm was employed to embolize the bilateral internal iliac and median sacral arteries, the smallest embolized artery was arteriole whose diameter was about 50 μm, but embolized arteries were mainly arterioles with a diameter of 100-200 μm. The first-class branches of embolized bilateral internal iliac and median sacral arteries were reserved which were displayed on the digital subtraction angiography. In addition, pelvic organs had no obvious pathological alteration.