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树脂渗透修复脱矿牙齿
引用本文:刘子晗,李 静,汤根兄,徐 疾,郑 红. 树脂渗透修复脱矿牙齿[J]. 中国组织工程研究, 2013, 17(47): 8196-8201. DOI: 10.3969/j.issn.2095-4344.2013.47.009
作者姓名:刘子晗  李 静  汤根兄  徐 疾  郑 红
作者单位:南京医科大学附属南京儿童医院口腔科,江苏省南京市 210008
摘    要:背景:树脂渗透技术是一种治疗早期龋的新方法,为评估其治疗效果,与传统再矿化治疗方法进行比较。目的:比较树脂渗透技术与氟化物再矿化治疗拮抗牙体组织脱矿的效果。方法:将35颗牛牙样本的釉质表面各制备出3个相同大小的窗区,分别设为渗透区、氟化钠区、空白区,将样本制备为脱矿模型,渗透区行树脂渗透处理(Icon®),氟化钠区每天以0.1%NaF溶液涂布连续7 d(即氟化物再矿化治疗),空白区不作处理;将样本自底部垂直向表面二等分,一份设为脱矿组再次脱矿,一份设为对照组置于去离子水中保存,观察脱矿组与对照组相对应窗区脱矿深度的进展。结果与结论:牛牙样本渗透区、氟化钠区脱矿深度的进展均小于空白区(P < 0.05),且渗透区脱矿深度的进展小于氟化钠区(P < 0.05)。提示树脂渗透技术和氟化物再矿化治疗均可抑制牙体组织进一步脱矿,树脂渗透技术拮抗脱矿效果可能更佳。

关 键 词:生物材料  组织工程口腔材料  牙齿脱矿  釉质龋  进展  牛牙釉质  渗透  牙齿再矿化治疗  氟化物  扫描电镜  

Resin infiltration for demineralized enamel
Liu Zi-han,Li Jing,Tang Gen-xiong,Xu Ji,Zheng Hong. Resin infiltration for demineralized enamel[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(47): 8196-8201. DOI: 10.3969/j.issn.2095-4344.2013.47.009
Authors:Liu Zi-han  Li Jing  Tang Gen-xiong  Xu Ji  Zheng Hong
Affiliation:Department of Stomatology, Nanjing Children’s Hospital, Nanjing Medical University, Nanjing  210008, Jiangsu Province, China
Abstract:BACKGROUND: Resin infiltration is a novel approach in treating non-cavitated caries lesions on smooth surfaces, and the effectiveness comparison between resin infiltration and remineralizing therapy is required.OBJECTIVE: To compare the effects of resin infiltration and remineralizing therapy on inhibition of non-cavitated lesions in vitro.METHODS: Three subsurface lesions were created on 35 bovine labial specimens. One of the lesions was permeated with Icon® infiltrant, one was applied by 0.1% NaF solution daily for 7 consecutive days, whereas one lesion remained as the untreated control. Subsequently, half of each specimen was covered with nail varnish (baseline) and the other half was re-exposed to a demineralizing solution for 5 days (experimental). The specimens were cut perpendicularly to the surface, stained with Rhodamine B and observed with fluorescence microscope.RESULTS AND CONCLUSION: For lesions permeated with Icon® infiltrant and applied by 0.1% NaF solution, the progression of lesion depth was significantly decreased (P < 0.05) compared with the untreated control. Lesions permeated with Icon® infiltrant got more significantly reduced lesion progression (P < 0.05) compared with the ones applied by 0.1% NaF solution. It can be concluded that both resin infiltration and remineralizing therapy have active effects on inhibition of non-cavitated lesions, and filling the pores with Icon® infiltrant can inhibit further demineralization even better.
Keywords:resins  synthetic  osmosis  dental enamel  bone demineralization technique  
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