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植骨融合联合内固定恢复胸腰椎骨折脱位后的椎体高度
引用本文:彭 俊,徐建广. 植骨融合联合内固定恢复胸腰椎骨折脱位后的椎体高度[J]. 中国组织工程研究, 2013, 17(31): 5729. DOI: 10.3969/j.issn.2095-4344.2013.31.024
作者姓名:彭 俊  徐建广
作者单位:上海交通大学附属第六人民医院骨科,上海市 200233
摘    要:背景:椎管减压植骨融合联合椎弓根钉系统内固定成为胸腰椎骨折脱位患者的主要治疗手段。目的:探讨经椎弓根行伤椎次全切除减压椎体钛笼加自体松质骨粒植骨融合支撑联合椎弓根钉系统内固定恢复胸腰椎严重骨折脱位患者的椎体高度。方法:选取2007年2月至2011年9月上海交通大学附属第六人民医院收治的胸腰椎严重骨折脱位患者31例,全部采用经椎弓根伤椎次全切除、椎管减压,钛笼加自体松质骨粒植骨融合支撑联合椎弓根钉系统内固定治疗。在治疗前后进行影像学检查,观察椎体序列的恢复以及椎体高度、Cobb角的恢复情况,同时观察神经功能恢复情况。结果与结论:随访12-30个月,所有患者椎体钛笼加自体松质骨粒植骨融合后均较好,椎弓根钉系统内固定无松动、脱落、断裂等。复查时植骨块均已融合,畸形矫正良好,椎体高度基本恢复,Cobb角恢复良好。7例神经功能有所恢复,其中6例提高1级,1例提高2级,另外22例未恢复。病例分析和相关研究结果说明,经椎弓根行伤椎次全切除减压,椎体间钛笼加自体松质骨粒植骨融合支撑联合椎弓根钉系统内固定,可以减少严重胸腰椎骨折脱位患者椎体矫正丢失,恢复椎体高度,增强椎体的稳定性。

关 键 词:器官移植  器官移植学术探讨  骨移植  椎体高度  胸腰椎骨折  植骨融合  神经功能  
收稿时间:2013-03-14

Bone graft fusion combined with internal fixation restores vertebral height after thoracolumbar fracture and dislocation
Peng Jun,Xu Jian-guang. Bone graft fusion combined with internal fixation restores vertebral height after thoracolumbar fracture and dislocation[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(31): 5729. DOI: 10.3969/j.issn.2095-4344.2013.31.024
Authors:Peng Jun  Xu Jian-guang
Affiliation:Department of Orthopedics, Shanghai 6th People’ s Hospital of Shanghai Jiao Tong University, Shanghai  200233, China
Abstract:BACKGROUND: Spinal canal decompression and fusion combined with pedicle screw fixation has become the main method for the treatment of thoracolumbar fracture and dislocation.OBJECTIVE: To restore the vertebral height of the patients with thoracolumbar fracture and dislocation who underwent subtotal resection and decompression through titanium cage packed with autologous cancellous bone and pedicle screw fixation. METHODS: Thirty-one patients with thoracolumbar fracture and dislocation treated in the Shanghai 6th People’ s Hospital of Shanghai Jiao Tong University from February 2007 to September 2011 were selected. All the patients received subtotal resection, spinal canal decompression and titanium cage packed with autologous cancellous bone and pedicle screw fixation. Imaging examination was performed before and after treatment to observe the recovery of vertebral sequence, vertebral height and Cobb angle, as well as the recovery of nerve function.RESUTLS AND CONCLUSION:The patients were followed-up for 12 months, and all the patients healed well after treated with titanium cage packed with autologous cancellous bone and pedicle screw fixation, and there was no loosening, shedding or breakage after pedicle screw fixation. During reexamination, the grafts fusion, good deformity correction, basic recovery of vertebral height and good recovery of Cobb angle were observed. Seven cases had neurological function recovery, and among them, six cases raised for one degree, one case raised for two degrees, and another 22 cases without recovery. Case analysis and relative researches showed that subtotal resection and decompression and titanium cage packed with autologous cancellous bone and pedicle screw fixation can reduce the loss of correction of the patients with thoracolumbar fracture and dislocation, restore the vertebral height, and enhance the stability of the vertebral body.
Keywords:organ transplantation  organ transplantation academic discussion  bone graft  vertebral height  thoracolumbar fractures  fusion  neurologic function  
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