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Natural taurine promotes apoptosis of human hepatic stellate cells in proteomics analysis |
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| Authors: | Xin Deng Jian Liang Zhi-Xiu Lin Fa-Sheng Wu Ya-Ping Zhang Zhi-Wei Zhang |
| Affiliation: | Xin Deng, Jian Liang, Fa-Sheng Wu, Ya-Ping Zhang, Zhi-Wei Zhang, The Affiliated Ruikang Hospital of Guangxi Traditional Chinese Medical University, Nanning 530011, Guangxi Zhuang Autonomous Region, ChinaZhi-Xiu Lin, School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China |
| Abstract: | AIM:To study the differential expression of proteins between natural taurine treated hepatic stellate cells and controls, and investigate the underlying regulatory mechanism of natural taurine in inhibiting hepatic fibrosis.METHODS: A proteomic strategy combining two-dimensional gel electrophoresis and ultraperform ance liquid chromatographyelectrospray ionizationtandem mass spectrometry (UPLCESIMS/MS) was used to study the differential expression of proteins and Western blotting was used to validate the re... |
| Keywords: | Natural taurine Proteomics Hepatic stellate cell Hepatic fibrosis Apoptosis |
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| 点击此处可从《World journal of gastroenterology : WJG》浏览原始摘要信息 | |