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Alkaloids from Aspidosperma species from Bolivia
Authors:Mitaine A C  Mesbah K  Richard B  Petermann C  Arrazola S  Moretti C  Zèches-Hanrot M  Men-Olivier L L
Institution:Faculté de Pharmacie (U.R.A. au C.N.R. S. no 492), 51, rue Cognacq-Jay, F-51096 Reims Cedex, France.
Abstract:Two Bolivian Aspidosperma species were investigated. The seed and stem bark of Aspidosperma macrocarpon Mart. contain six known alkaloids: (-)-vincadifformine, ervinceine, kopsanone, kopsinine, kopsanol in the seed, and kopsanone, kopsinine, kopsanol, 18-epikopsanol in the stem bark. The stem bark of Aspidosperma pyrifolium Mart. contains eleven known alkaloids: (-)-vincadifformine, O-demethylpalosine, haplocine, N-formylaspidospermidine, vallesine, demethoxyaspidospermine, palosine, (-)-aspidospermine, aspidospermidine, akuammicine, tubotaiwine, beside the two new bases dehydroxyhaplocidine and 10-methoxyaspidospermidine.
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