Spinal fusions: bone and bone substitutes |
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| Authors: | D G Marchesi |
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| Institution: | Department of Orthopaedic Surgery, Jewish General Hospital, Room-E, 003, 3755 Côte Ste Catherine, Montreal, H3T 1E2, Canada e-mail: dante@orl.mcgill.ca, , , , CA ;Division of Orthopaedic Surgery, McGill University, Montreal, Canada, , , , CA |
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| Abstract: | Vertebral arthrodesis is one of the most commonly performed, yet incompletely understood, procedures in spinal surgery. Despite
major progress in internal fixation techniques, the high rate of non-unions indicates that physiologic, biologic and molecular
events that are crucial to this process are not well known. This article will analyze the general biology of bone regeneration,
and particularly discuss the properties and use of various bone graft materials and graft substitutes.
Received: 9 August 2000/Accepted: 11 August 2000 |
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| Keywords: | Bone regeneration Spinal fusion Bone substitutes Growth factors |
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